External use of either xanthotoxin or umbelliferone alone in normal rats showed that the chromosomes of the myelocyte were mutated at an aberrant rate of 2.0 % and 0.2 % respectively ( P < 0.01 ) .

以正常大鼠为实验对象，观察单纯外用 花椒毒内酯，结香甲素，连续给药7d，致骨髓细胞染色体畸变率相应各达2%及0.2%。两者比较具显著性差异（P＜0.01）。

System suitability test : Under the above conditions resolution and theoretical plate number the peak of xanthotoxin was calculated .

系统适用性试验：在确定的 色谱条件下， 考察 花椒 毒素 色谱峰的分离度和理论板数。

System suitability test : Under above conditions the peak of xanthotoxin was separated well with the resolution of more than 1.5 and about 8.0 × 103 of theoretical plate .

系统适用性试验： 花椒 毒素 色谱峰的理论板 数约为8.0×103，与 其他 色谱 峰的分离度大于1.5。

Penetration kinetics of xanthotoxin across human skin and stratum corneum

花椒 毒素在人体皮肤及角质层中的渗透动力学探讨