tegafur

[tɪ'ɡæfə][tɪ'ɡæfə]

[医]替加氟,喃氟啶:一种供研究用的癌瘤化疗药物,为与四氢呋喃相连的氟尿嘧啶(5-FU),相当于5-FU活性代谢物中核糖及脱氧核糖部分,可起到5-FU贮存剂型的作用,临床应用与5-FU同

  • Influence of survival rate on postoperative tegafur adjuvant chemotherapy in patients with squamous cell carcinoma undergoing Ro resection

    术后 辅助化疗对Ro切除的食管鳞癌患者生存率的影响

  • Content determination of Tegafur in Tegafur Capsules by HPLC

    高效液相色谱法测定替加氟胶囊中 加氟的含量

  • The Safety Assessment of Tegafur Injection Combined with Chemotherapy for Digestive System Cancers

    注射液联合化疗治疗消化道肿瘤安全性评价

  • HPLC determination of Fluorouracil and related substances in Tegafur Injection

    HPLC法测定 注射液中的氟尿嘧啶等有关物质

  • A Study of Concurrent Versus Sequential Chemoradiotherapy with Tegafur and Cisplatin for Old Patients with Locally Advanced Esophageal Carcinoma

    放疗联合 顺铂同步或序贯化疗治疗老年晚期食管癌的临床研究

  • An UV simultaneous equations method has been developed for determination of tegafur and uracil in composite preparations using neutral buffer solution .

    在中性缓冲溶液中,用紫外分光解线性方程法,直接同时测定复方胶囊中 1)和尿嘧啶(2)的含量。

  • Clinical Effects of Radiotherapy Combined with Tegafur Suppository Treatment for Mid-to Late-Stage Esophageal Cancer

    放疗联合 栓同步治疗中晚期食管癌的临床研究

  • Objective : 1 . To observe the effectiveness and safety of a combination therapy of S-1 and Oxaliplatin in the treatment of advanced gastric cancer compared with a chemotherapy regimen of tegafur and Oxaliplatin .

    目的:1.比较复方 拉西胶囊(S-1)加草酸铂与替加 加草酸铂治疗晚期胃癌的近期疗效、毒副反应、临床获益反应和疾病进展时间、生存期。

  • Study of antitumor activity of conjugate of phospholipid with tegafur

    磷脂 缀合物抑瘤作用的研究

  • Studies on kinetics of hydrolysis of tegafur

    水解动力学的研究

  • Observation of curative effect of OXA united with Tegafur and Calcium Leucovorin for curing gastric and intestinal cancer

    草酸铂联合 及甲酰四氢叶酸钙治疗胃肠肿瘤的疗效观察

  • The Research on the Synthesis of Diselenides 、 Tegafur Diselenides and Organoselenium Sugars by the Catalysis of Cesium Ion

    铯离子催化下二硒醚、 二硒醚及有机硒糖的合成研究

  • Results : by comparison with the control group the mean tumor size and the expression of PCNA in Xiaoji decoction group and in the Tegafur group were reduced ( P 0 01 ) and the number of apoptosis cells increased ( P 0 01 );

    结果:消积饮组和 氟组平均瘤重、PCNA表达阳性率均低于生理盐水组(P001),凋亡细胞数目高于生理盐水组(P001);

  • Clinical observation of combined chemotherapy of tegafur and oxaliplatin for treatment of advanced gastric cancer

    联合奥沙利铂方案治疗晚期胃癌的疗效观察

  • Determination of tegafur and uracil in composite preparations by UV simultaneous equations method

    和尿嘧啶复方制剂的紫外分光解线性方程法测定

  • Objective To compare the efficacy and toxicity of oxaliplatin ( OXA ) and calcium folinate ( CF ) combined with tegafur or fluorouracil ( 5-FU ) to treat patients with advanced gastric caner .

    目的比较草酸铂联合亚叶酸钙、 方案与草酸铂联合亚叶酸钙、氟尿嘧啶方案治疗晚期胃癌的临床疗效和毒性。

  • Tegafur is a broad spectrum anticancer drugs it is mainly used in the treatment of gastric cancer colorectal cancer and so on .

    是一种广谱性的抗肿瘤药物,主要用于治疗胃癌、结直肠癌等。

  • Pharmacokinetics and liver targeting of tegafur magnetic long-circulating liposomes in rats

    磁性长循环脂质体在大鼠体内的药代动力学和靶向性

  • Objective To determine the maximum-tolerated dose ( MTD ) and dose-limiting toxicity ( DLT ) of tegafur and oxaliplatin in patients with gastrointestinal cancers .

    目的探索不同剂量方克( )联合草酸铂治疗胃肠道癌的最大耐受剂量(MTD)和剂量限制性毒性(DLT)。

  • In order to search novel 5-fluorouracil derivative antitumor drugs we designed and synthesized 20 novel tegafur containing phosphorus compounds .

    为了寻找新型的5-氟尿嘧啶类药物,本文以 氟为原料设计合成了20种 未见 文献 报道的含磷( 酸酯 氟的衍生物。

  • Study on small intestinal absorption of tegafur new proliposome in rat

    新型前体脂质体小肠吸收试验研究

  • Determination of tegafur in oral emulsion by second order derivative UV Spectrophotometry

    口服乳剂的二阶导数分光光度测定

  • Docetaxel Combined with Cisplatin and Tegafur in Treatment of Advanced Gastric Carcinoma

    多西他赛联合顺铂和 治疗进展期胃癌的临床分析

  • The tumor control rate both of Chinese medicinal formulae group and Tegafur group were higher than 30 % and there were no significant deviation between them ( P > 0.05 ) .

    中药组方组和 组的抑瘤率均大于30%; 中药 组方组与 组的抑瘤率无显著性差异(P>0.05)。

  • Results The mean quality of tumor in either of Chinese medicinal formulae group and Tegafur group was light than the normal saline group and there was significant deviation between them ( P < 0.01 ) .

    结果中药组方组和 小鼠 皮下肿瘤平均质量均比生理盐水组小,有显著性差异(P均<0.01);

  • Tegafur and gecko decoction could depress in value of esophageal cancer rates but the difference was not statistically significant .

    及壁虎水煎液均可在数值上降低食管癌变率,但差异无统计学意义;

  • CONCLUSION The simulated concentration-time curves of tegafur and its metabolite in plasma and tissue basically describe the activation process of tegafur into 5-FU and 5-FU elimination .

    结论血浆、乳腺肿瘤组织和 相邻 正常组织的药-时曲线拟合对 加氟转化为5-FU及5-FU消除过程进行了较好的描述。

  • RESULTS : GAG reinforced the antitumor effect of 5 FU or Tegafur in S180 or EAC mice and the inhibitory rates of tumor growth were 61.96 % ( S180 ) and 46.30 % ( EAC ) .

    结果:糖胺聚糖粗、精提取物分别对体内S180肉瘤和艾氏腹水癌(EAC)有显著增敏5FU或 的抑瘤作用,抑瘤率分别达61.96%或46.30%;

  • Efficacy comparison of tegafur or fluorouracil combined with oxaliplatin and calcium folinate to treat patients with advanced gastric cancer

    草酸铂及亚叶酸钙分别联合 或氟尿嘧啶治疗晚期胃癌疗效比较