Synthesis of 5 ′ tosyl derivatives of 2 ′ 3 ′ dideoxy nucleosides

三种脱氧核苷5′ -O- 对 甲苯 磺酸 酯的合成

Polyethyleneglycol ( PEG ) activated by tosyl chloride was used to modify penicillin acylase ( PAC ) . The stability of the PEG PAC was much better than the free PAC . The activity of the modified enzyme was 75 % of free enzyme .

采用 对 甲苯 磺 酰氯法，用聚乙二醇对青霉素酰化酶进行 化学修饰，修饰酶的比活为 未修饰酶的75%，稳定性比游离酶有了很大提高。

Determine the equivalent weight of the purified tosyl derivative by titration using a standardized solution of0.05M sodium hydroxide .

用，0.05M的氢氧化钠标准溶液，对已纯化的 对 甲基 苯 磺醯化的衍生物进行滴定，以确定其等当量。

The productivity of mono-6-O-tosyl β - cyclodextrin is promoted from 7 % 11 % reported in previous literature to about 18 % through changing the adding mode of tosyl chloride . The effect of reaction conditions on the productivity is also concerned .

通过改变6单 对甲苯磺酰基β环糊精合成方法中 对 甲苯 磺 酰氯的加入方式，将反应产率由文献报道的7%，11%提高到18%，并讨论了反应条件对产率的影响；

Inulinase from Aspergillus ficuum SK004 was immobilized on cotton cloth activated with p-toluenesulfonyl chloride ( tosyl chloride ) .

以4-甲苯磺 酰氯活化的棉纤维为载体，对固定化菊粉酶的条件进行探讨。