Objective To assess the efficacy and safety of sulindac on colorectal polyps .

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Analysis of 48 cases of esophageal cancer treated by sulindac stents combined radiotherapy

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Inhibitory effect of sulindac on the growth of gastric cancer cells in vitro

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Conclusion Sulindac has inhibitory effects on S180 and it decreases the expression of COX-2 in tumor tissue . There is positive relation between the expression of COX-2 and angiogenesis related factor .

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Experimental study for effect of sulindac for gastric cancer cell BGC - 823

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Background & aim : to study the effect of Sulindac on growth inhibition of human gastric cancer cells bgc_823 in vitro and its antineoplastic mechanisms .

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Nonsteroidal anti-inflammatory drugs ( NSAIDs ) such as aspirin indomethacin and sulindac showed by lots of evidence have the effect of suppressing tumor proliferation and inducing apoptosis besides its effect of anti-inflammation relieving pain and anti-coagulation of platelets .

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OBJECTIVE To observe the therapeutic effects of sulindac ( a new type of NSAIDs ) on experimental hypercalciuria and to clarify its pharmacological mechanism .

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Objective To assess the clinical efficacy of sulindac on familial adenomatous polyposis ( FAP ) and its possible mechanism .

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At last in the two systems of SDS-MECC and Tween 20-MECC the contents of sulindac and indometacin in tablets were determined and satisfactory results were obtained .

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Effect of sulindac on growth of transplantable ovarian carcinoma of nude mice model

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Conclusion The therapeutic effect of sulindac on FAP is not sure but it is effective on SCAP .

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Conclusions : Sulindac may inhibit the proliferation and induce apoptosis of colon cancer cell HT-29 and its mechanism probably relates to the progress of its prevention on cell cycle .

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Objective : To research the mechanism of sulindac affecting human colorectal cancer cells .

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Preparation and Clinical Application of Sulindac Chitosan Gel

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Influence of Sulindac on the Expressions of p53 bcl-2 and Bax in Mice Model with Colon Carcinoma

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In recent years Accumulating evidences have indicated that sulindac appears to reduce the risk of colorectal cancer decrease the incidence of familial adenomatous polyposis . Compared with other traditional nonsteroidal anti-inflammatory drugs sulindac has less adverse reactions .

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Sulindac Induced Apoptosis of HT-29 Colon Adenocarcinoma Cell

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Methods SGC-7901 cells were treated by sulindac and nimesulide . The anti-proliferative effect was measured by using MTT assay ; COX-2 and NF - u03ba B protein expression were examined by immunohistochemical stain and western-blot analysis .

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The Growth Inhibition of Colorectal Adenoma Cells by Sulindac and Its Mechanisms

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Objective : To observe the effect of Sulindac on changes of the apoptosis regulating genes in different stages of the tumor formation and probe the possible anticarcinogenic molecular mechanism of sulindac .

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ABSTRACTS OF ORIGINAL ARTICLE Relative bioavailability of sulindac capsules

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Effects of Sulindac on growth inhibition and apoptosis induction in human gastric cancer cells

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A study of the effects of PPAR u03b3 pathway on the proliferation inhibition of gastric cancer cells by sulindac and the underlying mechanism

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Conclusion The proliferation of SGC-7901 cells was inhibited after treated by sulindac and nimesulide . Suppressing COX-2 NF - u03ba B expression may play some roles in the antitumor process of these two drugs .

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Objective This study was conducted to assess the growth inhibition of colorectal adenoma cells by sulindac and identify the possible mechanisms .

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No severe adverse event was found during the treatment . Conclusions Long-term treatment of sulindac is effective in maintaining the regression of colorectal adenoma in FAP patients .

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A Study on the Apoptosis of BGC-823 Gastric Cancer Cells Induced by Sulindac

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