Elegant studies revealed that the special mechanism of SCOT catalyzing the formation of acetoacetyl CoA is generating the thioester with coenzyme A and binding the ADP groups of coenzyme A in the form of non – covalent bond .

研究表明：SCOT催化乙酰乙酰辅酶A生成的具体机制是与辅酶A的巯基生成 硫 酯并以非共价 键的形式连接辅酶A的ADP基团。