Preparation of the humanized anti-human thyroglobulin monoclonal antibodies

抗人 甲状腺 球 蛋白人源化单克隆抗体的制备

METHODS : Mice were immunized to induce autoimmune thyroiditis with porcine thyroglobulin ( pTg ) and thyroids of mice were injected with IL-10 DNA . On d 28 after immunization with pTg mRNA expression of IL-10 in thyroid glands was detected and thyroid specimens were histopathological studied .

方法：将IL-10质粒DNA注射入由猪 甲状腺 球 蛋白（pTg）诱发的自身免疫性甲状腺炎小鼠甲状腺内，pTg免疫后28天，进行甲状腺IL-10mRNA表达和组织学等检查。

The thyroglobulin gene and autoimmune thyroid disease

甲状腺 球 蛋白基因与自身免疫性甲状腺疾病

AIM : To identify the presence of previously reported thyroglobulin ( Tg ) gene single-nucleotide polymorphism ( SNP ) in Chinese people and to investigate their potential relation to the aetiology of autoimmune thyroid disease ( AITD ) .

目的检测中国人 甲状腺 球 蛋白（Tg）基因的外显子 10是否存在单核苷酸多态性（SNP），研究其与自身免疫性甲状腺疾病（AITD）的关系。

We determined serum levels of thyroglobulin ( TG ) in thyroglobulin antibodies ( TG-Ab ) positive patients with mono-clonal solid - phase method and double antibody radioimmunoassay .

应用单克隆固相放免法及双抗体法测定了自身免疫性甲状腺球蛋白抗体（TG-Ab）阳性病人血清中 甲状腺 球 蛋白（TG）浓度。

Three glycoproteins have been tested their inhibitory capacities in decreasing order were : porcine thyroglobulin human serum transferrin and hen ovalbumin .

三个所用的糖蛋白，它们的抑制活性 以下 列顺序递减：猪 甲状腺 球 蛋白，人血清转铁蛋白，鸡卵白蛋白。

The antigenicity analysis of human thyroglobulin with monoclonal antibodies

应用单克隆抗体分析 甲状腺 球 蛋白的抗原性

Results of serum thyroglobulin antibody and thyroid microsomal antibody measurement of 2687 patients and its clinical significance

2687例血清 甲状腺 球 蛋白抗体和微粒体抗体测定及其临床意义

Production and primary application of monoclonal antibodies to human thyroglobulin

抗人 甲状腺 球 蛋白单克隆抗体的研制和初步应用

As greater clinical correlation is obtained the usefulness of thyroglobulin determinations will increase .

随着 甲状腺 球 蛋白测定与临床的关系日益紧密，其 诊断价值也日益提高。

Influential Factors of Serum Thyroglobulin after Surgical Treatment of Differentiated Thyroid Carcinoma

分化型甲状腺癌患者术后血 甲状腺 球 蛋白 监测的影响因素分析

Methods Antibody to thyroglobulin ( TGAb ) and antibody to thyroid-peroxidase ( TPOAb ) were measured in 86 cases of subclinical hyperthyroidism by microparticle enzyme immunoassay ( MEIA ) control group was composed of 51 healthy people .

方法以51名健康人为对照，对86例亚临床甲亢患者用微粒子酶免疫法（MEIA）测定 甲状腺 球 蛋白抗体（TGAb）和甲状腺过氧化物酶抗体（TPOAb）。

The gelatinous product of the thyroid gland consisting mainly of thyroglobulin which serves as the precursor and storage form of thyroid hormone . Construction and Expression of Recombinant Fusion Protein hPTH ( 1-34 ) a'a-HSA

甲状腺囊中一种凝胶状物质，主要包含 甲状腺 球 蛋白，作为甲状腺分泌物贮藏处人甲状旁腺激素（1-34）二联体与人血清白蛋白融合蛋白的构建及表达

Association of thyroglobulin gene polymorphisms with autoimmune thyroid diseases

甲状腺 球 蛋白基因多态性与自身免疫性甲状腺病的相关性

Research on the value of thyroglobulin levels in pregnant women in preventing iodine deficiency

孕妇 甲状腺 球 蛋白水平 检测在碘缺乏病预防中的价值研究

The result of carbohydrate inhibition assay showed that Mannan and Thyroglobulin could inhibit the agglutinating activity of LRA .

糖抑制实验显示，甘露聚糖和 甲状腺 球 蛋白能有效抑制LRA的凝血活性。

Methods : The 9 cases with comparatively larger tumor sizes out of the 69 specimens were primary cultured in vitro . The expression of thyroglobulin ( TG )、 cytokeratin ( CK7 ) and ER by immunocytochemistry were detected .

方法：从69例标本中选取了9例肿瘤组织较大的标本进行原代培养，并且用免疫细胞化学方法检测细胞中 甲状腺 球 蛋白（TG）、角蛋白（CK7）、ER的表达。

Studies on Induction of Experimental Autoimmune Thyroiditis with Excessive Iodine and Thyroglobulin in Rats

碘和 甲状腺 球 蛋白诱导大鼠自身免疫性甲状腺炎的研究

Objective To investigate the correlation between serum thyroglobulin ( Tg ) and thyroid stimulating hormone ( TSH ) in populations with non toxic goiter .

目的探讨非毒性甲状腺肿人群血清 甲状腺 球 蛋白（Tg）和促甲状腺素（TSH）的相关性。

Gene expression of thyrotropin recepter thyroid peroxidase and thyroglobulin in autoimmune thyroid disease

促甲状腺激素受体、甲状腺过氧化物酶及 甲状腺 球 蛋白基因表达与自身免疫甲状腺疾病

An epidemiological study on factors affecting serum thyroglobulin levels

影响血清 甲状腺 球 蛋白水平因素的流行病学研究

Thyroglobulin and Thyroid ~ ( 99 ) mTc0_4 ~ - imaging for Clinical Diagnosis of Thyroid Nodules

甲状腺 球 蛋白与甲状腺~（99）mTc04~-显像对甲状腺结节临床诊断的分析

Objective The development of experimental autoimmune thyroiditis ( EAT ) was investigated by immunization of Wistar rats with human thyroglobulin ( hTG ) human thyroid peroxidase ( hTPO ) and guinea pig thyroid stimulating hormone receptor ( gTSHR ) .

目的观察人类 甲状腺 球 蛋白（hTG），人类甲状腺过氧化物酶（hTPO）以及豚鼠促甲状腺激素受体（gTSHR）免疫诱导Wistar大鼠产生实验性自身免疫性甲状腺炎（EAT）的过程。

Tg ( thyroglobulin ) is an established serum tumour marker in the follow-up of differentiated thyroid cancer .

Tg（ 甲状腺 球 蛋白）是非常重要的随访分化型甲状腺癌的血清肿瘤标志物。

An immunohistochemical study of thyroglobulin in thyroid carcinomas

甲状腺癌的 甲状腺 球 蛋白免疫组织化学研究

Correlation between serum thyroglobulin and thyroid stimulating hormone in populations with non-toxic goiter

非毒性甲状腺肿人群血清 甲状腺 球 蛋白和促甲状腺素水平相关性研究

A Clinical Laboratory Investigation of Serum Thyroglobulin

血清 甲状腺 球 蛋白的临床观测及应用研究

Objective investigate the relationship between degradation of thyroglobulin and postmortem interval ( PMI ) .

目的探讨 尸体 甲状腺 球 蛋白降解 程度与死亡时间（PMI）的关系。

Therapeutic effects were evaluated by131I whole body imaging 18F-FDG tumor imaging and levels of serum thyroglobulin and its receptor and adverse effects were also observed .

以131I全身显像、18F-FDG肿瘤显像及血清 甲状腺 球 蛋白及其抗体水平评价疗效，同时观察不良反应发生情况。