Results With the progress of oral carcinogenesis regular changes of epithelial cell were showed : decrease in tonofibril keratohyaline granules desmosome ; and increase in mitochondria .

结果随 大 鼠舌癌变进展， 鳞状上皮细胞 浆、 核、细胞间 连接、 基底 膜等发生规律性变化。其中张力原纤维、桥粒、角质颗粒呈逐渐减少 趋势，线粒体则逐渐增多；