CONCLUSION : Clinicians should pay attention to the toxity of tobramycin dexamethasone eye drops on cornea and prevention and treatment standard medication should be performed .

结论：临床医生应关注 妥布霉素地塞米松滴眼液对角膜的毒性作用，并积极预防和治疗，规范用药。

Tobramycin has some activity against several staphylococci and many Gram negative bacteria and is invalid to staphylococcus aureus staphylococcus epidermis some Gram negative bacteria and most anaerobes .

妥布霉素对一些葡萄球菌和多种革兰氏阴性菌有抗菌活性，对金黄色葡萄球菌、表皮葡萄球菌、一些革兰氏阴性菌和大多数厌氧菌无效。

Objective To evaluated the effect of 0.3 Tobramycin eye drop for Pseudomonas Aeruginosa corneal ulcer ( PACU ) .

目的观察用0.3% 妥布霉素 滴眼液治疗绿脓杆菌性角膜溃疡的临床疗效。

The influence of width between the supersolubility curve and solubility curve was investigated by regulating the concentration of tobramycin sulfate in the solution and agitation rate also with the ultrasonic apparatus .

考察了硫酸 妥布霉素在溶液中的浓度，搅拌速度以及超声波对硫酸妥布霉素超溶解度同溶解度宽度的影响，并考察了诱导期与过饱和度比的关系。

A new method was developed for the separation and determination of tobramycin in milk by HPLC using a C_ ( 18 ) column and pulsed integrated amperometric electrochemical detection .

采用C18 键 合 硅胶柱和脉冲积分安培电化学检测器对 妥布霉素 样品进行了分离检测。

CONCLUSION : The technology of Tobramycin eye drops production is simple therapeutic effect is satisfactory and the production in hospital is feasible .

结论： 妥布霉素 滴眼液制备工艺简单，疗效确切，可作为医院制剂推广。

Results of sensitivity to antibiotics showed that the strains were very sensitive to amikacin tobramycin norfloxacin and gentamicin but insensitive to penicillin carbenicillin and ampicillin .

用多种药物对分离的菌株进行药敏试验，结果表明，4个菌株对丁胺卡那、 妥布霉素、氟哌酸、庆大霉素高度敏感，对青霉素、羧苄青霉素、氨苄青霉素则不敏感。

Effect of Atomization Inhalation of Tobramycin on Lung Infection

妥布霉素雾化吸入治疗肺部感染效果观察

Ofloxacin tobramycin and gentamicin were high sensitivity in drug sensitive test .

药敏试验结果：敏感药物为氧氟沙星、 先锋 霉 素、庆大霉素等。

At pH 2.0 ~ 7.0 trypan blue ( TB ) reacted with aminoglycoside antibiotics such as kanamycin sulfate ( KANA ) and tobramycin sulfate ( TOB ) to form blue ion association complexes .

曲利本蓝（TB）与硫酸卡那霉素（KANA）和硫酸 妥布霉素（TOB）等氨基糖苷类抗生素在pH2.0～7.0的条件下反应生成蓝色离子缔合物。

Tobramycin delivery should avoid local excessive drug concentrations . 2 .

结论：1 、 妥布霉素缓释应避免局部过高药物浓度。

Color-fading reaction of methyl blue with gentamycin ( or tobramycin ) and Its Analytical Applications

甲基蓝与庆大霉素、 妥布霉素的褪色反应及其应用

At present the major topical treatment to eye infection in our country is quinolone eyedrop represented by ofloxacin and ciprofloxacin and aminoglycoside eyedrop represented by tobramycin .

目前国内在眼部感染的局部治疗方面主要使用氧氟沙星、环丙沙星为代表的喹喏酮类滴眼液和以 妥布霉素为代表的氨基糖甙类滴眼液。

Study on Scale up of Tobramycin Fermentation

妥 布拉 霉 素发酵 放大 规律的研究

Study on Antibacterial Activities of Tobramycin in Vitro

妥布霉素 伤 用 凝胶的体外抗菌作用研究

Methods 16 MRSA and 24 MSSA strains were used in this study . The aminoglycoside resistant genes were detected by PCR and aminoglycoside resistance was tested by Kirby-Bauer method to 4 kind of antibiotics ( Amikacin Gentamicin Netilmicin Tobramycin ) .

方法运用K-B法和PCR方法分别对16株MRSA和24株MSSA4种氨基糖苷药物（丁胺卡那霉素、奈替米星、庆大霉素 、 妥布霉素）耐药性和氨基糖苷类耐药基因进行检测。

All of the strains were 100 % sensitive to Ofloxacin Tobramycin and Kanamycin as well as Rifabutin ( 40 % ) while Cefuroxime and Carbenicillin was not sensitive at all .

结果显示，所有的菌株对氟嗪酸、 妥布霉素和卡那霉素均100%敏感，对利福平的敏感率也较高（40%），而对于头孢呋新、羧苄青霉素的耐药率则分别高达100%和80%。

Antimicrobial susceptibility tests of amikacin gentamicin tobramycin and netilmicin in 20 multi-drug resistant Pseudomonas aeruginosa were detected by agar diffusion .

用琼脂扩散法检测20株多重耐药铜绿假单胞菌对阿米卡星、庆大霉素、 妥布霉素和奈替米星4种药物的敏感性。

Clinical study on cefazolin and tobramycin for treating the bacterial corneal ulcer

头孢唑啉钠与 妥布霉素 联合 应用治疗细菌性角膜溃疡的临床观察

The two main types of aminoglycoside-modifying enzymes were ANT ( 2 ″) and AAC ( 3 ) - II which were associated with the resistance to gentamycin and tobramycin .

推测主要氨基糖苷修饰酶为ANT（2〃）和AAC（3）Ⅱ，引起庆大霉素和 妥布霉素耐药。

OBJECTIVE : To assess the feasibility of production and effects of Tobramycin eye drops prepared in this hospital for treating ocular infections .

目的：对我院 妥布霉素 滴眼液进行制备和临床疗效观察，评价其生产的可行性与确切的临床疗效。

Streptomyces tenebrarius H_6 produces a complex of aminoglycoside antibiotics such as apramycin tobramycin and kanamycin B etc.

tenebrariusH6产生多种氨基糖苷类抗生素，主要有阿泊拉霉素、 妥布霉素及卡那霉素B。

Clinical study on tobramycin and dexamethasone eye drops for bacterial blepharitis

妥布霉素地塞米松滴眼液治疗细菌性眼睑炎症的临床研究

Conclusion Tobramycin eye drops is safety for clinic application .

目的 考察 妥布霉素 滴眼液的安全性。

Objective To observe the effects of calcium phosphate cement with tobramycin ( CPC T ) on traumatic osteomyelitis .

目的观察 含有 硫酸 妥布霉素的磷酸钙骨水泥（ CPC-T）对外伤性骨髓炎的疗效。

Application of stirring with changing velocity in tobramycin fermentation

变速搅拌在 妥布霉素发酵中的应用

Objective To compare the aqueous humor penetration of topically applied ofloxacin ciprofloxacin and tobramycin in human eyes .

目的比较人眼滴用氧氟沙星、环丙沙星及 妥布霉素的前房穿透性差异。

Suitable tobramycin concentration for injectable antibiotic DBM is50mg / ml.3 .

注射型抗感染骨 妥布霉素适宜浓度为50mg/ml。

CONCLUSION : Domestic and imported compound tobramycin eye drops and eye ointment has same antibacterial effect in the treatment of bacterial conjunctivitis and fine anti-inflammatory effect in the recovery process of cataract extracted patients .

结论：国产复方妥布霉素 滴眼液和眼膏对白内障术后炎症控制和细菌性结膜炎疗效明显且安全，与进口复方 妥布霉素滴眼液和眼膏相似。

Twenty isolates resistant to amikacin gentamicin tobramycin and netilmicin were 35.0 % 90.0 % 70.0 % and 60.0 % respectively .

20株菌对阿米卡星、庆大霉素、 妥布霉素和奈替米星的耐药率分别为35.0%、90.0%、70.0%、60.0%。