The results show that the Maximum tolerance dose ( MTD ) which is orally administered once by the mice is higher than 20g / kg . Pathologic study finds that toxic target apparatus is liver . No abnormality reactions are found in acute dermal toxicity test .

结果表明，小鼠1次口服海洋低温碱性蛋白酶的 MTD>20g/kg为 实际无毒物，其中毒的靶器官是肝脏，未见大鼠经皮的急性毒性反应。

The dose limiting toxicity ( DLT ) o f it was neutropenia and diarrhea . Its maximum tolerance dose ( MTD ) may be reduced by elevated liver or kidney function .

其剂量限制毒性（DLT）为中性粒细胞减少和腹泻，肝肾功能下降会降低最大 耐受 剂量（MTD）。

Metho ds : Mice acute toxicity test ( median lethal dose minimum lethal dose maximum tolerance dose );

方法：小鼠急性毒性实验（半数致死量、最小致死量、最大 耐受 量）；

The maximum tolerance dose of mice was 205.2 times of that in human .

小鼠最大 耐受 量为人 用量的205.2倍。

The oral maximal tolerance dose was greater than 105 g / kg .

口服最大 耐 量超过105g／kg。

Result : The acute toxicity showed that the max tolerance dose of rabbit pituitary injection was 24 ml · kg - 1 which corresponded to 300 times of human dose .

结果：急性毒性实验表明：小鼠未出现异常反应，其最大 耐受 量为24ml·kg-1，相当于临床人用剂量的300倍。

Exercise tolerance dose of serum lactic acid and muscle biopsy are important for diagnose of MELAS syndrome .

确诊需要乳酸运动 耐 量试验及肌肉活检。

Acute toxicity test showed that maximum tolerance dose ( MTD ) of mice to Tribute Health Wine was 270ml / kg .

经NIH小鼠急性毒性实验测定结果表明，贡品健身酒最大 耐受 量为270ml/kg。

Results No toxicity of Gen-seng oral tablet to the mice was observed when the maximum tolerance dose of Gen-seng oral tablet increased to 20000mg / kg BW ;

结果西洋参含片用最大 耐受 量达20000mg/Kgbw时，对小鼠无毒性作用；

The biological effect and physiological function requirements tolerance toxic dose of copper in dairy cattle were reviewed .

本文就铜的生物学效应和生理功能，奶牛对铜的需要量、 耐受 量和中毒 量等进行阐述。

It was confirmed the deviation of Th1 / Th2 could induce tolerance in low dose group .

给予低 剂量抗原可引起Th1/Th2分泌的细胞因子发生偏离，产生 免疫 耐受。

METHODS Mice were used in acute toxicity experiments . Oral LD 50 and maximal tolerance dose ( MTD ) were determined and the doses for human being were calculated accordingly .

方法：急性毒性实验用小鼠以口服和腹腔给药，分别测定 LD50 和 MDT，并推算出相当临床人用量的倍数。

But he suggested that what could be obtained now are data about partial organ tolerance and dose constraints .

而他认为我们现在只能获得关于局部器官 耐受 性 和 剂量限制的数据。

To observe the acute toxicity and death of the mice to which calcium nanoparticles were given in maximal dose and obtain the lethal dose 50 ( LD50 ) or the maximal tolerance dose ( MTD ) .

观察小鼠一日内给予大剂量钙纳米粒子的急性中毒及死亡情况，得出半数致死量（LD50）或最大 耐受 量（MTD）。

Acute toxicity : The maximum tolerance dose of FZTS per day is larger than 40.0g/kg in mice .

小鼠急性毒性：FZTS小鼠灌服最大 耐受 量大于40.0g／kg。

Pharmacokinetics and tolerance of single dose intravenous drip of ginsenoside-Rd injection in Chinese healthy volunteers

单 次静滴人参皂苷-Rd注射液在中国健康志愿者的药代动力学及 耐受 性

That fine tolerance to single dose of famciclovir and pharmacokinetic charateristics similar to Famvir showed that famciclovir in a dose of 0.125g ~ 0.75g 3 times daily would be safe for clinical use .

单 剂量口服泛昔洛韦良好的 耐受 性和药动学特点的事实，推荐口服泛昔洛韦0－125g～0－75g、1日3次的给药方案用于临床可能是安全的。

In toxicology research median lethal dose ( LD50 ) and maximum tolerance dose of LG ( ig ) were observed .

毒理学研究观察了灌胃给药途径的狼疮静颗粒LD（50）及最大 耐受 量试验。

The maximum tolerance dose of oral administration of this drug in mice was 80ml / kg body weight .

小鼠口服该药的最大 耐受 量为80ml/kg体重。

The acute toxicity test of tigogenin showed that its maximum tolerance dose was 4.5 g / kg .

急性毒性实验表明，其最大 给 药量为 4.5g/kg。

Methods According to the mechanism of motion disease relative receptor antagonists were selected as the compound preparations and acute toxicity ( LD50 ) or maximal tolerance dose ( MTD ) of the preparations was tested .

方法根据运动病的发病机理，选择相关的受体拮抗剂进行组方并进行动物急性毒性（ LD50）或最大 耐受 性试验。

But due to an insulating layer in its structure the tolerance of total dose irradiation of SOI is poorer than normal silicon material .

但由于绝缘埋层的引入，使得材料本身的 抗总 剂量辐照 能力反而不如体硅材料。

IMRT can significantly decrease the maximum exposure dose and average exposure dose to the spinal cord compared with 3D-CRT ( P 0.05 ) but neither of the two plans exceed the maximum tolerance dose of spinal cord .

IMRT减少了脊髓最大受照剂量和平均受照剂量，较3D-CRT降低了脊髓的受量。且两者有统计学差异（P0.05）但两种计划均未超出脊髓的最大 耐受 剂量。

A Study of the safety on the maximum tolerance dose of the sodium lactate Ringer intraperitoneal injection in mice

小鼠腹腔注射乳酸钠林格液最大 耐受 量的研究

When LD50 could not be measured because of lower toxicity the maximum tolerance dose ( MTD ) was measured with the highest concentration 300 % and the largest volume 0.3ml/10g by irrigating gastric ( ig ) for 3 times in one day .

若毒性很小，测不出LD（50），则改用一日内以 小鼠能 耐受的最大浓度300%和最大容积0.3ml／10g，灌胃3次，测定最大给 药量。

CONCLUSION The method is simple accurate specific and it could be used for quality control of Bisoprolol fumarate tablets . Tolerance dose of homemade bisoprolol fumarate tablets and its effects on left ventricular functions

结论所用方法简单、准确、经济、专属性强，可用于富马酸比索洛尔片中有关物质及含量的测定。国产富马比索洛尔 耐受 量及其对心功能的影响

AIM : To investigate the relationship between astroglial activation state and ischemic tolerance induced by low dose of 3 nitropropionic acid ( 3 NPA ) in gerbil hippocampus .

目的：探讨海马区星形胶质细胞的激活与3硝基丙酸（ 3NPA）预处理诱导脑缺血 耐受的关系。

The toxic test suggested that the maximal tolerance dose of mice with its extract a day was 220 times as much as clinical administration dose .

毒性试验表明，小鼠一天 口服王老吉浸膏最大 耐 量为临床口服量的220倍。