In 2004 we had initially performed PH3-10 gradient 2-DE of chronic sinusitis nasal polyps and normal nasal mucosa tissue and found isoelectric point ( PI ) of most proteins is between PH 4-8 .

在前期研究中，我们在国内外领先进行了慢性鼻窦炎、鼻息肉和正常鼻粘膜 组织的PH3-10差异蛋白质组研究，发现大多数 蛋白质的等电点（PI）在PH4～8的范围。

The data suggested that the combination of the local cardiac tissue ald with its receptor could induce increases in the synthesis of the myocyte proteins leading to myocyte hypertrophy in SHRs by activating the cardiac MAPKs .

提示醛固酮与其心脏受体结合并激活MAPKs，进而介导 SHRs心肌细胞 蛋白合成增加及心肌细胞肥大。

Conclusions : Two-dimensional electrophoresis and MALDI-TOF-MS are effective means in the protein profiling analysis of white adipose tissue the differentially expressed proteins may play an important role during the development of obesity and type 2 diabetes and serve as a new target of diabetes therapy .

结论双向凝胶电泳技术和MALDI-TOF-MS是进行脂肪 组织蛋白质组研究的有效手段，分析表达差异的 蛋白质可以进一步明确肥胖症、2型糖尿病病因，为药物治疗提供新的靶点。

Nimodipine can relieve cerebral tissue damage and increase expression of the two proteins and protect cells from damage .

尼莫通可以增加这两个 生长 因子的表达，起到神经保护作用。

Objective : To establish the two-dimensional electrophoresis profiles with high resolution and reproducibility from human lung squamous carcinoma tissue and paired normal tumor-adjacent bronchial epithelial tissue and to identify differential expression tumor-associated proteins by using proteome analysis .

目的利用蛋白质组学方法建立人肺鳞癌组织及其癌旁正常支气管上皮 组织的差异 蛋白质表达谱。

Based on the results that the variation of these secretory proteins in trophoblastic tissue as pregnancy advanced we suggested that these proteins may play different physiological role during the early pregnancy .

有可能这些 蛋白质在 妊娠过程中起着不同生理作用，所以在不同周龄中的合成量亦有变化。

Differential expression of colonic tissue proteins in mice induced by extract of senna

番泻叶提取物诱导小鼠结肠 组织 中 蛋白质的差异表达

Methods : According to tissue types and neural invasive ability of SACC the expression of Slit and Robo proteins were detected with ( immunohistochemical ) assay from 34 cases .

方法：对34例SACC进行 组织分型、嗜神经性分组，同时应用免疫组化方法，对SACC中 Slit/Robo的表达进行检测。

Candida albicans can synthesize and secrete a great number of toxic molecules and immune-modulating molecules itself They can involve in fungal adhesion degrade of host tissue proteins and regulate the morphological conversion process of Candida albicans .

白色念珠菌本身能分泌和合成大量的毒性分子和免疫调节因子，它们参与真菌的粘附、降解宿主 组织 蛋白、调节白色念珠菌形态转换等过程。

The research on other tissue and cell have demonstrated that integrin and G proteins play an important role in the mechanical regulation however such research on condylar cartilage have not been seen .

在其他 组织、细胞的研究表明整合素、G 蛋白在力学调控机制中起到重要作用，而在髁突软骨组织的研究尚未见报道。

This review introduced the structure action mechanism the developmental expression tissue localization and chromosome mapping of retinal-binding proteins and its relationship with reproductive traits and embryonic development .

本文主要就血清及细胞内视黄醇结合 蛋白的基因结构、作用机理、发育性表达、 组织定位及染色体定位、对动物繁殖性能和胚胎发育的影响等方面进行综述。

Second-and third-trimester serum and placental tissue levels of placental proteins in normal pregnant women and patients with pre-eclampsia at term

正常妊娠孕妇和子痫前期患者妊娠中晚期血清和 胎盘中妊娠相关 蛋白浓度的变化

Methods The Se containing proteins in testis of the rat were investigated by in vivo labeling with 75 Se selenite separation of the tissue homogenate proteins by SDS PAGE and determination of the labeled proteins by γ detector and γ counter .

方法采用 75Se活体标记、SDS-PAGE和γ射线探测等技术研究睾丸 组织中含硒蛋白的分布。

At the same time tissue expression of goose PRLR shows that there are three PRLR proteins existed in adult female goose tissues and they may be the canonical PRLR protein and PRLR isoforms . 3 .

同时， 组织表达分析表明，成年母鹅组织中至少存在三种PRLR 蛋白，它们或许是经典的PRLR蛋白及PRLR的蛋白异形体。

The fibrotic response which is characterized by a striking increase in fibroblast population a profound and complex change in ECM turnover is generally considered an irreversible process leading to a progressive accumulation of connective tissue proteins or basement membrane disruption in early stage of the disease .

肺纤维化反应表现为成纤维细胞数量的明显增加，细胞外基质转换失衡，一般认为是一种不可逆的过程。在疾病早期可有富含结缔 组织 的 蛋白沉积和基底膜破坏。

Tissue inhibitors of metalloproteinases ( TIMPs ) are multifunctional proteins that can modify cellular activities and modulate matrix turnover .

金属蛋白酶 组织抑制剂（TIMPs）是多功能 蛋白，能改变细胞活性和调节基质转变。

Working with brain tissue from people who had FTD the researchers got rid of low-molecular-weight soluble proteins .

研究人员采用额颞痴呆患者的脑 组织作研究，并从中弃去了低分子量和可溶性 蛋白质。

Biochemical Properties and Tissue Distribution of Two Kinesin-like Proteins ( KatB / KatC ) in Arabidopsis

拟南芥中两种动 蛋白异型体KatB/KatC生化性质及 组织分布研究

Protein expression profiles were obtained from the preneoplastic lesion and HCC tissue in the rat hepatocarcinogenesis induced by DEN . Eighty-two proteins were screened and identified some of which were firstly reported . 3 .

获得了DEN诱发的大鼠肝癌前病变组织和肝癌 组织的蛋白质表达谱，共筛选出82 种 差异 表达 蛋白质，其中部分蛋白质在肝癌相关研究中为新报道。

Under stress conditions MSC home to sites of injury whereby they decrease local inflammation and participate to tissue repair and regeneration by secretion of cytokines chemokines and extracellular matrix proteins .

在受到炎症信号刺激的情况下，MSC会募集到发生炎症损伤的部位，通过分泌细胞因子，趋化因子和细胞外基质 蛋白质，降低局部炎症损伤，参与到局部 炎症部位的修复和再生。

This shows the binding ability of different pathogenic form IBV strains with the various tissue cell membrane proteins differs significantly and the differences may be related with the change of IBV tissue tropism . 5 .

这说明不同致病性IBV毒株与各 组织细胞膜 蛋白的结合力存在差异，且该差异可能与IBV的组织嗜性变化有关。

Based on the carbonyl stress hypothesis of aging a variety of reactive carbonyl intermediates the common products of the Maillard reactions and advanced lipid peroxidation reactions can affect the oxidative modification of tissue proteins directly .

基于羰基毒害衰老理论，具有强烈反应活性的羰基类化合物是非酶糖基化和脂质过氧化的共同中间产物，它们是造成 蛋白修饰的直接原因之一。

Insoluble proteins in spinal cord tissue may also play crucial roles after SCI . By studying these proteins we could get more theoretical information which is significant for research .

脊髓 组织中的难溶 蛋白在脊髓损伤后可能也起着关键的作用，它们可以为我们提供更多的理论信息，具有重要的研究意义。

This review introduces action mechanism tissue localization and developmental expression of retinol-binding proteins . This review also introduces the structure chromosome mapping and their relationships with reproductive performance of retinol-binding protein genes .

介绍了视黄醇结合 蛋白的作用机理、 组织定位和发育性表达，还介绍了 视黄醇结合蛋白基因的结构、染色体定位以及与动物繁殖性能的关系。

They are major components of adipose tissue and together with proteins and carbohydrates they constitute the principal structural components of all living cells .

它们和 蛋白质、碳水化合物是脂肪 组织的主要成分，它们是构成所有活细胞的主要结构成分。

CDNA microarray results demonstrated that the expression of genes encoding adhesion molecules tissue remodeling proteins transporters and ribosomal proteins were up regulated in ATRA treated of HL 60 cells .

基因表达谱分析发现，黏附分子、 组织重建 蛋白、转运蛋白、核蛋白体蛋白和涉及氧化酶激活途径的基因表达明显升高。

Proteomics is a genome an organism a cell tissue expressed proteins and their interactions of all of the information provided a more realistic reflection of genes tissues organs the actual functional status .

蛋白质组学是对一个基因组、一种生物、一种细胞、 组织所表达的全部 蛋白质及其相互作用的研究，提供的资料更真实地反映基因、组织、器官的实际功能状态。

The result indicated that the designed recombinant protein was not significant homology with human tissue proteins and had similar second structure and 3D structure with the naive M protein and was hydrophilic . B cell epitopes in every fragment containing different serotype sequences had not been changed .

软件分析结果表明，设计蛋白与人体 组织 蛋白无同源性，亲水性好，与天然M蛋白空间结构相似，四个血清型的氨基酸序列拼接之后原有抗原表位未被改变。

One induced aborted fetal liver tissue ( 19 wk of pregnancy ) was detected having the proteins and DNA of HBV . CONCLUSION There may be two intrauterine transmission routes hematogenous and cellular transfer routes .

1例孕19wk引产胎儿肝 组织中检出HBVdna和 抗原.结论胎儿宫内感染的发生可经2条途径，即血源性和细胞性。

Tissue transglutaminase ( tTG ) is capable of cross - linking ECM proteins to proteolysis - resistant complexes . It has important functions in ECM accumulation and scar formation .

组织型转谷氨酰胺酶（tTG）能催化ECM 蛋白之间形成抗蛋白酶水解的交联，在ECM的沉积和瘢痕形成过程中起重要作用。