HPLC method was established for the determination of the trans-isomer and R-isomer of mitiglinide calcium .

建立了HPLC法测定 米 格列奈钙的 反 式 异构 体和R-异构体。

Among them the physiologically active of trans-isomer is stronger than the cis-isomer the monomer activity greater than the glucoside .

其中， 反 式 异构 体生理活性强于顺式异构体，单体的活性大于糖苷。