Inhibitory effects of triethyltin chloride on proliferation of rat C6 glioma cells in vivo and morphological changes

氯化 三 乙基 锡对体内大鼠C6胶质瘤增殖抑制作用及病理学改变

Effect of Triethyltin Chloride on Proliferation and Ultrastructure Changes of Cultured Rat C6 Glioma Cells in Vitro

超微形态学观察 氯化 三 乙基 锡 抗体外培养大鼠C6脑胶质瘤增殖作用

We can detect typical morphologic changes of apoptosis in C6 glioma cells treated by 2.0 μ M triethyltin for 48h by HE coloration .

HE染色观察到2.0μM 氯化 三 乙基 锡作用于C6胶质瘤细胞48h后， 出现细胞凋亡特有的形态学改变。

Conclusion Triethyltin chloride can inhibit the proliferation of cultured rat C6 glioma cells and induce its apoptosis .

结论 氯化 三 乙基 锡可抑制体外培养C6胶质瘤细胞增殖并诱导细胞凋亡。

Methods MTT colorimetry optical microscope and HE coloration were used to examine the inhibitory effect of triethyltin chloride on the proliferation of C6 glioma cells .

方法采用四甲基偶氮唑盐（MTT）比色法检测氯化 三 乙基 锡对C6胶质瘤细胞的增殖抑制作用，采用 普通倒置显微镜和HE染色形态学方法 观察氯化三 乙基 锡对C6细胞增殖抑制作用。