Objective To investigate the feasibility of overage and overweight rats as an alternative to rabbits in the experiment of uropoietic influence factors .

目的探讨超龄超重大鼠代替家兔进行 尿 生成影响因素实验的可行性。

Macrolides which are used for the treatment of the infections of respiratory system digestive system and uropoietic system in clinical application led to serious bacterial resistance because they were abused . This became major threat to successful treatment of infectious diseases .

用于治疗呼吸道感染和 皮肤 软 组织感染的大环内酯类抗生素由于其在临床的 广泛使用， 特别是滥用，导致许多细菌对该类抗生素产生了严重的耐药性，给临床治疗带来了 极大困难。