The patients ' glomerular filtration rate and renal plasma flow have decreased before the increase of the serum creatinine and usea nitrogen which is called subclinical HRS which is could not be diagnosed by the normal renal function detection .

肝硬变患者在血肌酐、 尿素 氮升高之前，就已经存在肾小球滤过率和肾血流量的下降，称为亚临床HRS，常规的肾功能检查不能识别。