Prokaryotic expression and polyclonal antibody preparation of human platelet glycoprotein ⅵ extracellular domain

人血小板膜糖蛋白 VI胞外区片段的原核表达及多克隆 抗体的制备

Preparation and characterization of a monoclonal antibody directed against platelet glycoprotein VI

抗血小板糖蛋白 VI单克隆 抗体的制备及其功能研究

Compared to pre immunization the level of sera LPS antibody in each Vi Vaccine inoculated group was significantly high in 1 month after vaccination ( P < 0.001 ) While in the control group showed no significant difference ( P > 0.2 ) .

各 Vi多糖菌苗组免疫后1月，6月的 抗LPS水平均显著高于免前（P＜0.0001），对照组无显著差异（p＞0.1）。

To develop a potential antithrombotic reagent a single chain antibody ( scFv ) from monoclonal antibody ( McAb ) SZ118 against platelet glycoprotein VI was prepared .

将抗血小板膜表面糖蛋白 VI（GPVI）单克隆抗体SZ118构建成单链 抗体，以研究开发新型抗血栓药物。