Development of Synthesis of Steroid Drugs from Tigogenin in China

我国 利用 剑麻 皂素合成甾体药物的研究进展

The acute toxicity test of tigogenin showed that its maximum tolerance dose was 4.5 g / kg .

急性毒性实验表明，其最大给药量为 4.5g/kg。

At present China can get tigogenin byproduct of hemp producing industry 500 tons per year from the waste water of hemp making industry . If we can not make rational utilization of tigogenin heavily polluting the environment must be happen .

目前我国每年能够从制麻工业废水中获取制麻工业的副产物 - 剑麻 皂甙 元500吨，如果不能合理利用这些皂甙资源而直接抛弃到自然界中，必然会对环境造成的很大的危害。

Tigogenin is a byproduct in the hemp-making industry using the sisal as a castoff it pricks up environmental pollutant .

剑麻 皂甙 元 是 剑麻 制麻工业的副产物，丢弃到环境中加剧了对环境的 危害。如何合理利用剑麻 皂甙 元，消除剑麻制麻工业中的污染问题迫在眉睫。

Methods : A study was made of the effect of using silica gel and macroporous resin I as absorbent in column chromatography on the separation of tigogenin .

方法：研究用硅胶、大孔树脂Ⅰ作为吸附剂的柱色谱的分离 效果。