Theobromine caffeine and theophylline are zanthine methylium derivates . They have the similar mother structure but different on the number of replaced methylium and its place .

可可碱 （Theobromine）、咖啡因 （Caffeine）、茶碱 （Theophylline）是 黄嘌呤甲基衍生物，它们的母体结构相同，只是甲基取代基的数目和位置不同。

The SOD activity and the MDA level in granulosa cells were measured by the methods of zanthine hydrocarbonylation and thio-malonylurea . 4 .

采用 黄嘌呤 氧化酶法和硫代巴比妥（TBA）法检测颗粒细胞的SOD活性和MDA含量。