Among them the symmetrical substituted compound 2 and 6 had higher activity than mono - substituted compound 3 4 and 7 . Especially compounds 2a-2f remarkably exhibited higher inhibition in comparison with artemisinin and artesunate .

青蒿素母核 对称取代2和6的活性高于青蒿素母核单取代的3和7。 化合物2a~2f的活性比青蒿素、青蒿琥酯高。