Epithelial-mesenchymal transition ( EMT ) occurs during critical phases of embryonic development in many animal species . It also play an important role in tumor formation and evolution .

上皮-间充质转变（EMT）是胚胎细胞在发育过程中重要的生物学行为，这一现象在 肿瘤 的 形成与演进中也扮演了重要角色。

And in vivo miR-34a also remarkably inhibits the capacities of in situ tumor formation and pulmonary metastasis . 4 .

动物实验中，miR-34a对骨肉瘤的原位 成 瘤能力和肺转移能力同样有显著的抑制作用。

Background : Tumor suppressor gene negatively control cell growth proliferation and differentiation . Loss of its functions caused by gene deletion and / or mutation contribute to cell transformation and tumor formation .

背景：抑癌基因负性调节细胞的生长、增殖及分化，如果出现基因缺失、突变等异常使其功能丧失，则会导致细胞 恶性转化而 发生 肿瘤。

Four cases of Multiple Myeloma ( MM ) with extramedullary tumor formation were presented .

本文报告4例多发性骨髓瘤伴有髓外 肿块 形成。

The Influence of mCD99L2 ~ - A20 Cells and T Cells to Tumor Formation and Analysis of Biological Information

mCD99L2~-A20细胞与T细胞对 成 瘤的影响及生物信息学分析

Also ADAMs has been reported to play an important role in tumor formation invasion and metastasis in both animal models and cancer patients .

既然ADAMs家族基因已经被报道在动物模型和癌症患者中 肿瘤 的 形成、侵袭和转移中占有重要的一席之地。

Reducing the expression of Survivin gene will help to inhibit normal cell proliferation and reverse tumor formation .

通过调低该基因的表达有助于抑制细胞增殖，逆转 肿瘤 形成。

After using antisense technology to reduce cells expression of OPN the cell survival rate in soft agar decline so as to the rate of nude mice tumor formation and the ability of distant metastasis .

用反义核酸技术降低细胞中OPN的表达后，细胞软琼脂生存率下降，裸鼠成 瘤率和 发生远处转移的能力降低28 w_1302。

Any pathogenesis interfering with proliferation-death mediating mechanism will induce excessive proliferation and / or inhibition of apoptosis result in abnormal cell accumulation and tumor formation .

当任何一种致病因素干扰了细胞增殖和／或凋亡的调控机制，导致细胞过度增殖和／或凋亡抑制，都会造成细胞的异常蓄积，以致 形成 肿瘤。

HRG is an activator of the HER-2 oncogene promoting breast cancer growth and tumor formation in laboratory models .

HRG是HER-2原癌基因的激动子，在动物模型中促进乳癌细胞的生长和 肿瘤 的 形成。

Not only the transplantation of ESC but also the transplantation of ESC-derived differentiated cells would result in the tumor formation .

不仅是ESC的移植会导致 肿瘤的生成，ESC来源的分化细胞移植也可能会有 肿瘤 形成的风险。

The alarm bell halts the process of cell division in its tracks preventing an error that could lead to runaway cell division and eventually tumor formation .

警报使细胞分裂停止，以防止可能引起细胞分裂失控&最终导致 肿瘤 形成的错误发生。

Activation of AMPK can suppress tumor formation and inhibit cell growth in addition to lowering blood glucose levels .

AMP活化蛋白激酶的激活不但可降低血糖水平，而且可抑制 肿瘤 形成，阻止 肿瘤细胞生长。

To construct an osteosarcoma in situ tumor formation and pulmonary metastasis model and then evaluate the effects of miR-34a on the capacities of in situ tumor formation and pulmonary metastasis . 4 .

构建裸鼠的骨肉瘤原位 成 瘤肺转移模型，并进一步研究miR-34a对骨肉瘤细胞原位成瘤能力和肺转移能力的影响。

However patients with chronic injury also develop liver cancer opening the possibility that the stem cells are involved in tumor formation .

尽管如此，慢性肝损伤的患者也可以发展为肝癌，因为损伤加大了干细胞 形成 肿瘤的可能性。

Record the time of tumor formation size morphology texture and activity .

记录成 瘤时间并 计算 成 瘤 率， 观察 移植 瘤大小、形态、质地及活动度。

Persistent activation of G-CSF signaling induces tumor formation in hematopoietic system .

造血干细胞中G-CSF信号通路持续过度激活可导致血液系统 肿瘤 的 发生。

Through the tumor-bearing mice models we found that the tumor formation were affected by BEAL which had an effect obvious on anti-tumor under a certain conditions . 4 .

通过荷瘤小鼠模型，发现BEAL影响了 肿瘤 的 形成，在一定条件下具有明显的抑瘤作用。

Cancer stem cells are the cause of tumor formation recurrence and metastasis .

肿瘤干细胞是 肿瘤 形成、复发与转移的根源。

For the past few years researchs in the metastasis mechanism of breast cancer reveal the important function of integrin-mediated signal in tumor formation growth invasion and metastasis .

近年来对乳腺癌转移机制研究显示：由整合素介导的细胞间及与细胞外基质的相互作用等信号事件在 乳腺 肿瘤 形成、生长、侵袭、转移诸多过程中起了重要作用。

Effects of a Vascular Targeted Peptide ( GX1 ) on Tumor Formation and Angiogenesis and the Underlying Mechanisms

胃癌血管内皮靶向肽GX1在 肿瘤 生长及血管生成中的作用及机制研究

Detection of tumor formation rate in nude mice post inoculation .

检测裸鼠接种后的 成 瘤率。

The proliferation of HeLa cells in vitro and in vivo was determined by clone formation assay MTT assay and subcutaneous tumor formation in nude mice .

克隆形成实验、MTT法和裸鼠皮下 瘤 形成实验分别检测细胞克隆 形成率及细胞在体外和体内的增殖情况。

Lung adenocarcinoma stem cells proliferated obviously and posseses the ability of tumor formation . 3 .

分离的肺腺癌干细胞具有较强的增殖能力和致 瘤能力。

Recently the research that BLyS is relevant to human immunologic diseases especially to B cell tumor formation and development is still in the starting stage . This kind of research has been becoming a new focus as the diagnosis and treatment of immunologic diseases .

目前关于BLyS与人免疫性疾病，尤其是与B细胞 恶性 肿瘤 形成和发展关系的研究尚处于起步阶段，正成为其诊断和治疗研究的一个新热点。

Nuclear receptors are involved in regulating gene expression in development cell proliferation differentiation and apoptosis physiological substance metabolism and tumor formation .

它们与机体的生长发育，细胞的增殖、分化与凋亡，以及体内众多生理、物质代谢及 肿瘤 形成 过程中基因表达的调控有很大关系。

Precancerous injuries of BRL cells could cause the microenvironment change which can enhance the ability of tumor formation migration and invasion .

BRL细胞非致瘤性损伤可改变微环境，从而增强 肿瘤 细胞 的 成瘤、迁徙和侵袭能力。

Memory CTL needs T H cells to completely regress the development of tumor formation .

记忆性CTL的完全抑 瘤活性需要抗原特异性TH细胞的辅助。