Two Suitable Developing Solvents for Isolating Tyr and Cys by Paper Chromatography

胱氨酸和 酪氨酸纸层析分离的理想展开剂

AIM : To inhibit the expression of tyrosinase gene in murine B16 melanoma cells by antisense nucleotide .

目的：用反义核酸技术抑制小鼠B16黑色素瘤细胞酪氨酸酶基因（ tyr）的表达。

Objective To establish a method to assay phenylalanine ( Phe ) and tyrosine ( Tyr ) by tandem mass spectrometry and to observe the changes of human blood Phe and Tyr levels and Phe / Tyr ratio in the subjects withphenylketonuria ( PKU ) PKU heterozygotes and normal controls .

目的建立串联质谱技术测定血苯丙氨酸（Phe）和酪氨酸（ Tyr）浓度方法，观察苯丙酮尿症（PKU）、PKU杂合子和正常对照组血Phe、Tyr浓度及其比值（Phe/Tyr）变化。

This compound would notably affect the residual activity of the sample .

该化合物对 Tyr样品的残余紫外活性S有着显著的影响，使得S的剂量效应遵循一特殊规律。

Objective To investigate the effects of insulin receptor substrate ( IRS ) - 1 and its serine ( Ser ) ~ 307 phosphorylation and tyrosine ( Tyr ) phosphorylation on insulin resistance in skeletal muscle cells in the state of sepsis .

目的研究不同程度感染大鼠骨骼肌胰岛素受体底物-1（IRS-1）及其丝氨酸（Ser307）磷酸化和酪氨酸（ Tyr）磷酸化在胰岛素抵抗（IR）中的作用。

CaBP 21 has 46 % of hydrophobic amino acid ( with Gly without Trp ) content 10 % of basic amino acid content and 44 % of acidic and polar amino acids .

CaBP21中疏水性氨基酸（计Gly，不计Trp）约占46%，碱性氨基酸10%，酸性氨基酸与极性氨基酸约44%。CaBP21有较高的Ser、 Tyr含量。

Just one thing : what 's in it for tyr ?

只有一个问题：有多少 获胜 的 希望？

The leucine and tyrosine transported by the fish intestine at various concentrations accumulated gradually with time .

鲫鱼肠道对各浓度下的Leu和 Tyr转运量随时间逐步上升；

Although both Ser / Thr and Tyr phosphorylation play a crucial role in cellular regulation in animals only Ser / Thr phosphorylation has been proved to be an important regulatory mechanism in plant cells .

Ser/Thr和 Tyr磷酸化在动物和酵母细胞的生长发育过程中都起重要的作用，但在植物细胞中仅确立了Ser/Thr磷酸化作用。

Tyr the Even-Handed God of Justice .

提尔，公正之手，正义之神。

We introduce the architecture of our Tyr Engine conceptually in the second chapter .

本文第二章将会从概念上详细介绍 Tyr引擎的架构。

Methods Tyrosine ( Tyr ) hydrazide and Glycyl Tyr were injected into the uteri of preimplantation rats .

方法宫腔注射 酪氨酰肼及甘氨酰酪氨酸，检测早孕大鼠子宫胞浆雌二醇受体含量。

Tyrosinase a copper-containing enzyme . plays a key role in melanin metabolism and catecholamine synthesis .

酪氨酸酶（ TYR）是一种含铜酶，是黑素代谢和儿茶酚胺合成的关键酶。

Then we show the architecture and some implements of the Tyr Shading Engine from top view .

然后，本文再从上层详细分析了 TyrShadingEngine的结构和实现；

Don 't tyr to go against his principles .

别想反对他的原则。

The △ FosB protein might be located in nucleus with 16 Ser 5 Thr and 5 Tyr which probably be protein kinase phosphorylation sites .

△FosB蛋白质最大可能位于细胞核内，蛋白上有16个Ser，5个Thr，5个 Tyr，可能成为蛋白激酶磷酸化的位点。

Tyrosinase ( TYR ) is a copper-containing enzyme as known as polyphenol oxidase which is widely distributed in microorganisms plants and animals and involved in some pigment biosynthesis .

酪氨酸酶（ EC1.14.18.1）是一种含铜的氧化还原酶，它广泛存在于动植物和微生物中，与生物体内的一些色素合成直接相关。

Tyr do I strike you as some sort of starry-eyed dreamer ?

tyr，我让你觉得我是某种幻想家吗？

In adult skins IGF ⅰ R was mainly located in the cell membrane of epidermal cells while P Tyr was chiefly distributed in epidermal cells and some fibroblasts .

在成人皮肤中，IGFⅠRα、β主要分布于表皮细胞的细胞膜上，而P Tyr主要定位于表皮细胞和部分成纤维细胞中。

The Bioinformatics Study on TYR Gene Mutations and Its ' Pathogenic Mechanism in OCA1 Patients

OCA1患者 TYR基因突变及其致病机理的生物信息学初步研究

Proteins such as bovine serum albumin ( BSA ) are good reductants due to their 21 Tyr residues .

牛血清白蛋白（BSA）分子由于其含有21个具有还原性的 酪氨酸残基可作为一种优良的还原剂。

Conclusion Quantification of Phe and Tyr in blood filter spots by tandem mass spectrometry is fast and reliable .

结论串联质谱技术能够准确测定干血滤纸片中Phe和 Tyr浓度。

The TRP-1 TRP-2 and TYR are similar in structure and have more than 40 % amino acids homology .

TRP-1、TRP-2与 TYR在结构上相似，并具有40%以上的同源氨基酸。

In Norse mythology there was a god named Tyr .

在挪威神话里，有一个神名叫 蒂尔 （ TRY ）。

Therefore Cornus officinalis extracts were proved to inhibit the melanin synthesis by inhibiting TYR activity and degrading mRNA expression of TYR TRP-1 and TRP-2 .

可见，山茱萸提取物能够抑制 TYR活性和下调TYR、TRP-1和TRP-2mRNA的表达量，从而抑制正常人黑素细胞中黑素合成。

Results : The results showed that EGCG inhibited melanin synthesis and tyrosinase activity significantly compared with control .

结果：EGCG显著抑制黑素合成和 TYR活性，且呈浓度依赖性；

Tyr and Phe residues were close to the silver surface but the vibrations of side - chains of Trp residues were markedly enhanced .

Trp、 Tyr和Phe残基侧链靠近银表面、以Trp残基侧链的振动增强效应最显著。

Oleanolic acid also could increase tyrosinase activity and melanogenesis and compared with its control the mRNA level of TYR and TRP-1 increased 31.88 % and 17.73 % respectively ;

齐墩果酸也能明显激活酪氨酸酶（P＜0.01），促进黑素合成（P＜0.05），并使黑素细胞 TYR和TRP-1mRNA表达量分别比加入无水乙醇的对照增加31.88%和17.73%；

The phosphorylation assay proves that aldose reductase is the substrate of insulin-receptor tyrosine kinase and the Tyr ( 40 ) and Tyr ( 49 ) are phosphorylated by the kinase .

通过磷酸化实验证明：醛糖还原酶是胰岛素受体酪氨酸蛋白激酶的底物，经分析揭示：胰岛素受体酪氨酸蛋白激酶可将醛糖还原酶的 第40位和第49位的 酪氨酸残基磷酸化。

N immunohistochemical study on C-FOS C-JUN and phosphotyrosine ( p-Tyr ) cancer gene products was performed .

对97例肺癌进行了癌基因产物C－FOS、C－JUN、Phosphotyrosine（以下称P－ Tyr）的免疫组织化学研究。